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Free Shipping with the purchase of at least $75 of products by Doctor's Best. Some restrictions apply. Read Details Doctor's BestBest Lutein
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Best Lutein features Biolut™ Marigold extract, a potent source of lutein standardized to contain 90% lutein esters, equivalent to 45% free lutein. Marigold flowers are the most abundant source of lutein in nature. The esterified lutein in Biolut™ Marigold extract is easy to absorb and highly bioavailable. Each capsule provides 20 mg of free lutein.
Lutein is a yellow member of the carotenoid family. It is one of the major carotenoids found in human blood, with a high tissue concentration in the retina (and macula) of the human eye. Lutein functions as a potent free radical scavenger in a number of tissues, including the eyes, skin, heart and lungs. BenefitsMaintains Healthy Visual FunctionIt has been well established that lutein is present in high concentrations in the retinal tissue of the human eye. However, a study was conducted in human volunteers to determine whether taking lutein in supplement form actually increased the density of the carotenoid pigments present in the macula. In this study of eight individuals, researchers estimated the density of the macular pigments prior to having each individual take 10 mg of lutein daily in supplement form for 12 weeks. Plasma lutein concentrations were measured at 4-week intervals. During the course of the study, plasma levels increased five-fold from pre-supplement measures. It was also shown that macular pigment density increased by an average of 5.3% after 4 weeks due to increased deposition of lutein in optical tissues. A second study compared the oral bioavailability of esterified lutein, the form in Best Lutein, versus non-esterified lutein in 18 human volunteers. Serum levels of lutein were measured at particular timepoints after consumption of a single dose of lutein. Researchers found that in these individuals, the lutein ester formulation was nearly 62% more bioavailable than non-esterified lutein, as determined by a higher mean area under the curve (AUC) and higher serum concentrations. A study was also conducted to investigate the possible role of specific nutrients in protecting the lens of the eye against aging, a risk factor for compromised visual function. The study was comprised of 376 individuals aged from 18 to 75. Of the nutrients measured, it was found that the lenses of individuals with higher concentrations of lutein and zeaxanthin showed less of an effect from the aging process. The investigators concluded that these carotenoids may play a protective role in supporting the maintenance of healthy vision. In addition, a double-blind placebo controlled trial was performed in ninety individuals who had signs of compromised visual function. Individuals were divided into three groups and received either 10 mg lutein, 10 mg lutein plus a multivitamin/multimineral formulation, or placebo for 12 months. In both the lutein and lutein plus other nutrients groups, improvements were seen in mean eye macular pigment optical density, visual acuity and contrast sensitivity. No improvements were noted in the placebo group. These results demonstrate lutein’s beneficial effect on maintaining healthy visual function. Potent Antioxidant Protection Most of the beneficial effects of lutein are ascribed to its potent free radical scavenging abilities. It is well-known that lutein is a carotenoid related to beta-carotene and possesses antioxidant activity against a number of reactive oxygen species. More direct evidence for the free radical scavenging activity of lutein is found in studies of its effects on human lens epithelial cells. Cell cultures were exposed to ultraviolet light after pretreatment with lutein or alpha-tocopherol. Both nutrients were found to reduce ultraviolet-induced damage to lens epithelial cells. However, lutein was shown to have significantly higher photoprotective activity than alpha-tocopherol6, demonstrating its potential as a high-powered antioxidant. A further review of the mechanisms of lutein in conferring a protective role reveals evidence for its antioxidant activity in various body tissues. Lutein has been shown to be an effective antioxidant in vitro as well as in experimental models of a number of body systems. Diverse clinical benefits Evidence from various experimental trials suggests that lutein may play a protective role on the circulatory and cardiovascular systems. Its antioxidant activity may also extend to the heart, skin, lungs and blood vessels, making it a nutrient with diverse clinical benefits. Lutein possesses the ability to promote the health of many body tissues.
Other Ingredients:Modified cellulose (vegetarian capsule), cellulose, magnesium stearate (vegetable source), silicon dioxide. Product Notes:
Contains nothing other than listed ingredients. Packaged Weight:0.3 lbs. Manufacturer Info:
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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