The Benefits of DIM-Plus™

DIM-Plus™ contains diindolymethane, a phytonutrient found in cruciferous vegetables including broccoli, brussels sprouts, cabbage, cauliflower and kale. Unlike other plant nutrients such as soy isoflavones, diindolymethane has unique hormonal benefits. It supports the activity of enzymes that improve estrogen metabolism. Scientific research shows diindolylmethane increases the level of "good" estrogens (2-hydroxyestrogen) while reducing the level of "bad" estrogens (16-hydroxyestrogen).

The DIM-Plus™ Difference

• Patented Complex: DIM-Plus™ contains BioResponse-DIM™ and its patented, enhanced bioavailability delivery system for diindolymethane.
• Enhanced Absorption: The bioavailability of DIM-Plus™ is superior to regular diindolylmethane and its unstable precursor, indole-3-carbinol (I3C). With DIM-Plus you are assured a stabilized dose and consistent benefit from each capsule.
• Extra Cruciferous Vegetables: DIM-Plus™ also contains the unique Protectamins® cruciferous vegetable blend (spinach, cabbage, and concentrated broccoli powders) for added phytonutrients.

Healthy Estrogen Metabolism for Women and Men

Estrogen imbalance. It's a major contributor to perimenopause, premenstrual syndrome and unhealthy prostate glands. In fact, changing estrogen levels are relevant both to women and men.

Medical research shows these midlife concerns are not due to estrogen itself, but to problems with estrogen metabolism. Fortunately, leading experts have discovered natural nutrients that help restore estrogen balance. One such nutrient, diindolylmethane, actually helps promote healthier estrogen metabolism when it's consumed in a highly absorbable form.

What is diindolylmethane, and what are its benefits?

Diindolymethane is an indole plant nutrient found in cruciferous vegetables including broccoli, cabbage, brussels sprouts and cauliflower. Yet unlike other plant nutrients such as soy isoflavones, diindolylmethane has unique and distinct hormonal benefits. It supports the activity of specific enzymes that improve estrogen metabolism. Scientific research shows diindolylmethane increases the level of "good" estrogens (2-hydroxyestrogen) while reducing the level of "bad" estrogens (16-hydroxyestrogen).

The health benefits of "enhanced absorption" diindolylmethane are four-fold:

1. promotes healthy estrogen metabolism.
2. relieves PMS symptoms.
3. promotes fat loss.
4. supports healthy breast, cervical, uterine and prostate tissues.

Why enhanced absorption?

Diindolylmethane is normally insoluble in water and fats, making it poorly absorbed by the body. But when combined with vitamin E and phosphatidylcholine, then microencapsulated, diindolylmethane becomes bioavailable. Nature's Way DIM-plus™ is a unique formula containing the patented, "enhanced absorption" form of diindolylmethane developed by Michael A. Zeligs, M.D.

How is diindolylmethane different than indol-3-carbinol?

Indole-3-carbinol (I3C) is the unstable and inactive precursor to diindolylmethane. I3C first has to be converted into diindolylmethane while in the digestive tract in order to become active. The degree of conversion can vary significantly depending upon each individual's stomach acid pH level, diet and other physiological factors. Just how much diindolylmethane you're getting from I3C is unpredictable. But with Nature's Way DIM-plus™, you are assured a consistent dose of diindolylmethane with each and every capsule.

Why not just eat more cruciferous vegetables?

To get the same health benefit as two capsules of Nature's Way DIM-plus™, you would have to eat nearly two pounds of raw or lightly cooked broccoli. For many people, broccoli is delicious, but try to eat that amount consistently everyday!

What is the proper dose of DIM-plus™

In his paperback book, All About DIM (Avery, 2000), Dr. Zeligs recommends women take 100 to 200 mg of "enhanced absorption" diindolylmethane daily.

For fat loss he notes a daily dose of 300 mg was helpful as part of an overall weight management program. Men, however, should take up to 400 mg per day when they are engaged in exercise training programs.

With Nature's Way DIM-plus™ it's easy to match Dr. Zeligs' recommended dosage as each serving contains 100 mg of "enhanced absorption" diiindolylmethane, plus and additional 100 mg of Protectamins® cruciferous vegetable blend.

About Michael Zeligs, M.D.

Dr. Zeligs graduated form the University of California, Santa Barbara, and received his postgraduate medical training from the University of California, Irvine, College of Medicine. His research interests include nutrition and promoting healthy aging.